Transcription and Histone Modifications in the Recombination-Free Region Spanning a Rice Centromere[W]
نویسندگان
چکیده
منابع مشابه
Transcription and histone modifications in the recombination-free region spanning a rice centromere.
Centromeres are sites of spindle attachment for chromosome segregation. During meiosis, recombination is absent at centromeres and surrounding regions. To understand the molecular basis for recombination suppression, we have comprehensively annotated the 3.5-Mb region that spans a fully sequenced rice centromere. Although transcriptional analysis showed that the 750-kb CENH3-containing core is ...
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15 صفحه اولActive transcription without histone modifications.
Gene expression is regulated by proteins such as transcription factors, as well as by chromatin modifications on DNA and histones. Some histone modifications have been associated to transcriptional activation (i.e. H3K4me1, H3K4me3, H3K9ac, H3K27ac or H3K36me3) whereas others with gene silencing (H3K9me3 and H3K27me3). However, and challenging this premise, we have identified a set of genes in ...
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چکیده ندارد.
15 صفحه اولS region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
Immunoglobulin class switch recombination is governed by long-range interactions between enhancers and germline transcript promoters to activate transcription and modulate chromatin accessibility to activation-induced cytidine deaminase (AID). However, mechanisms leading to the differential targeting of AID to switch (S) regions but not to constant (C(H)) regions remain unclear. We show that S ...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2005
ISSN: 1532-298X
DOI: 10.1105/tpc.105.037945